| Item Type | Name |
|
Concept
|
Adenoviruses, Human
|
|
Concept
|
Haplorhini
|
|
Concept
|
Adenylyl Cyclases
|
|
Concept
|
Cyclic AMP
|
|
Concept
|
Amniotic Fluid
|
|
Concept
|
Bombesin
|
|
Concept
|
Aging
|
|
Concept
|
Antigens, Polyomavirus Transforming
|
|
Concept
|
Antiviral Agents
|
|
Concept
|
Chromatography, DEAE-Cellulose
|
|
Concept
|
Chromosome Banding
|
|
Concept
|
Analysis of Variance
|
|
Concept
|
Antibodies, Monoclonal
|
|
Concept
|
Chromosomes, Human, Pair 8
|
|
Concept
|
Asthma
|
|
Concept
|
Antigens, Viral, Tumor
|
|
Concept
|
Base Sequence
|
|
Concept
|
Cell Count
|
|
Concept
|
Benzopyrans
|
|
Concept
|
Biotin
|
|
Concept
|
Carcinoma, Renal Cell
|
|
Concept
|
Bacitracin
|
|
Concept
|
Butadienes
|
|
Concept
|
Endoribonucleases
|
|
Concept
|
Cattle
|
|
Concept
|
Cell Division
|
|
Concept
|
Flavonoids
|
|
Concept
|
Uterine Cervical Neoplasms
|
|
Concept
|
Chick Embryo
|
|
Concept
|
Chromosome Mapping
|
|
Concept
|
Codon
|
|
Concept
|
Genetic Vectors
|
|
Concept
|
Glycerides
|
|
Concept
|
Cricetulus
|
|
Concept
|
Cyclohexanes
|
|
Concept
|
Chromatography, Ion Exchange
|
|
Concept
|
Histamine
|
|
Concept
|
Hormones
|
|
Concept
|
Culture Media
|
|
Concept
|
Cysteine
|
|
Concept
|
Dactinomycin
|
|
Concept
|
Cornea
|
|
Concept
|
Imidazoles
|
|
Concept
|
Cycloheximide
|
|
Concept
|
Cysteine Endopeptidases
|
|
Concept
|
Dexamethasone
|
|
Concept
|
Injections, Intraperitoneal
|
|
Concept
|
Insulysin
|
|
Concept
|
Drosophila
|
|
Concept
|
DNA, Neoplasm
|
|
Concept
|
DNA, Recombinant
|
|
Concept
|
Electrodes
|
|
Concept
|
Electrophoresis, Polyacrylamide Gel
|
|
Concept
|
Genes, Regulator
|
|
Concept
|
Genetic Code
|
|
Concept
|
Kidney Neoplasms
|
|
Concept
|
Electrophysiology
|
|
Concept
|
Enzyme Inhibitors
|
|
Concept
|
Estradiol
|
|
Concept
|
Ethers, Cyclic
|
|
Concept
|
Diglycerides
|
|
Concept
|
Chromatography, High Pressure Liquid
|
|
Concept
|
Chromosomes, Human, Pair 10
|
|
Concept
|
Chromosomes, Human, Pair 9
|
|
Concept
|
Exons
|
|
Concept
|
Conjunctiva
|
|
Concept
|
Drosophila melanogaster
|
|
Concept
|
Drug Therapy, Combination
|
|
Concept
|
Fibroblasts
|
|
Concept
|
Interferons
|
|
Concept
|
Introns
|
|
Concept
|
Egtazic Acid
|
|
Concept
|
Enzyme Activation
|
|
Concept
|
Moloney murine leukemia virus
|
|
Concept
|
Gene Expression Regulation
|
|
Concept
|
Genes, Dominant
|
|
Concept
|
Glioma
|
|
Concept
|
Genes
|
|
Concept
|
Fibronectins
|
|
Concept
|
Nucleic Acid Hybridization
|
|
Concept
|
Obesity
|
|
Concept
|
Oncogenes
|
|
Concept
|
Hippocampus
|
|
Concept
|
Hemin
|
|
Concept
|
DNA Topoisomerases, Type I
|
|
Concept
|
Drug Combinations
|
|
Concept
|
Hydrogen Peroxide
|
|
Concept
|
Hydrogen-Ion Concentration
|
|
Concept
|
Hypertrophy
|
|
Concept
|
Liver Neoplasms
|
|
Concept
|
Electroretinography
|
|
Concept
|
Enzyme-Linked Immunosorbent Assay
|
|
Concept
|
Enzyme Induction
|
|
Concept
|
Genetic Carrier Screening
|
|
Concept
|
Escherichia coli
|
|
Concept
|
Fluorescent Antibody Technique
|
|
Concept
|
Immunosorbent Techniques
|
|
Concept
|
Interleukin-1
|
|
Concept
|
Isoenzymes
|
|
Concept
|
Light
|
|
Concept
|
Macrophages
|
|
Concept
|
Mammary Glands, Animal
|
|
Concept
|
Membrane Glycoproteins
|
|
Concept
|
Carcinoma, Hepatocellular
|
|
Concept
|
Metalloendopeptidases
|
|
Concept
|
Metformin
|
|
Concept
|
Hydrolysis
|
|
Concept
|
Mice, Transgenic
|
|
Concept
|
Models, Genetic
|
|
Concept
|
Immunohistochemistry
|
|
Concept
|
Pancreatic Neoplasms
|
|
Concept
|
Mice, Inbred BALB C
|
|
Concept
|
Mice, Inbred C57BL
|
|
Concept
|
Mice, Nude
|
|
Concept
|
Receptors, Estrogen
|
|
Concept
|
Molecular Biology
|
|
Concept
|
Mutation
|
|
Concept
|
Cricetinae
|
|
Concept
|
Phosphatidylinositols
|
|
Concept
|
Ovarian Neoplasms
|
|
Concept
|
Endopeptidases
|
|
Concept
|
Microscopy, Electron
|
|
Concept
|
Monensin
|
|
Concept
|
Pigment Epithelium of Eye
|
|
Concept
|
Phosphoprotein Phosphatases
|
|
Concept
|
Peptide Mapping
|
|
Concept
|
Piperazines
|
|
Concept
|
Plasmids
|
|
Concept
|
Protein Processing, Post-Translational
|
|
Concept
|
Protease Inhibitors
|
|
Concept
|
Protein Synthesis Inhibitors
|
|
Concept
|
Glutamine
|
|
Concept
|
Rabbits
|
|
Concept
|
Receptor, Insulin
|
|
Concept
|
Radiation Injuries, Experimental
|
|
Concept
|
Rauscher Virus
|
|
Concept
|
Spasms, Infantile
|
|
Concept
|
ROC Curve
|
|
Concept
|
Cohort Studies
|
|
Concept
|
Rats, Inbred Lew
|
|
Concept
|
Regulatory Sequences, Nucleic Acid
|
|
Concept
|
Retina
|
|
Concept
|
Cadherins
|
|
Concept
|
Interleukin-6
|
|
Concept
|
Thymidine
|
|
Concept
|
Humans
|
|
Concept
|
Leukemia, Radiation-Induced
|
|
Concept
|
Tretinoin
|
|
Concept
|
Inositol
|
|
Concept
|
Tumor Necrosis Factor-alpha
|
|
Concept
|
Testis
|
|
Concept
|
Genetic Variation
|
|
Concept
|
Iodine Radioisotopes
|
|
Concept
|
Ultraviolet Rays
|
|
Concept
|
Kinetochores
|
|
Concept
|
Weight Loss
|
|
Concept
|
Rett Syndrome
|
|
Concept
|
Gene Library
|
|
Concept
|
Glutamic Acid
|
|
Concept
|
Cell Culture Techniques
|
|
Concept
|
Drug Resistance, Neoplasm
|
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
|
Concept
|
Caspases
|
|
Concept
|
Guanine Nucleotide Exchange Factors
|
|
Concept
|
Mitogen-Activated Protein Kinases
|
|
Concept
|
Transforming Growth Factor beta
|
|
Concept
|
HMGA2 Protein
|
|
Concept
|
Up-Regulation
|
|
Concept
|
Normal Distribution
|
|
Concept
|
Genes, Tumor Suppressor
|
|
Concept
|
Genes, Wilms Tumor
|
|
Concept
|
G1 Phase
|
|
Concept
|
Antigens, CD
|
|
Concept
|
3T3 Cells
|
|
Concept
|
Microinjections
|
|
Concept
|
Cysteine Proteinase Inhibitors
|
|
Concept
|
Culture Media, Conditioned
|
|
Concept
|
Paclitaxel
|
|
Concept
|
Rats, Sprague-Dawley
|
|
Concept
|
Mutagenesis, Site-Directed
|
|
Concept
|
Sequence Alignment
|
|
Concept
|
T-Lymphocyte Subsets
|
|
Concept
|
Microscopy, Immunoelectron
|
|
Concept
|
RNA Interference
|
|
Concept
|
Alternative Splicing
|
|
Concept
|
Sequence Analysis, DNA
|
|
Concept
|
Methionine
|
|
Concept
|
Genes, Immediate-Early
|
|
Concept
|
Genes, Reporter
|
|
Concept
|
Mice, Obese
|
|
Concept
|
Paraffin Embedding
|
|
Concept
|
Treatment Outcome
|
|
Concept
|
Genomic Instability
|
|
Concept
|
Point Mutation
|
|
Concept
|
Gene Deletion
|
|
Concept
|
Sequence Deletion
|
|
Concept
|
MAP Kinase Kinase 1
|
|
Concept
|
MAP Kinase Kinase 2
|
|
Concept
|
Mice, Knockout
|
|
Concept
|
Adenovirus E3 Proteins
|
|
Concept
|
Crystallography, X-Ray
|
|
Concept
|
Gene Expression Regulation, Developmental
|
|
Concept
|
DNA, Complementary
|
|
Concept
|
Cell Proliferation
|
|
Concept
|
Phosphatidylethanolamine Binding Protein
|
|
Concept
|
Chemokines
|
|
Concept
|
Thapsigargin
|
|
Concept
|
ras Proteins
|
|
Concept
|
Apoptosis Regulatory Proteins
|
|
Concept
|
Antineoplastic Agents, Alkylating
|
|
Concept
|
Staurosporine
|
|
Concept
|
BRCA1 Protein
|
|
Concept
|
Fas Ligand Protein
|
|
Concept
|
Gene Regulatory Networks
|
|
Concept
|
ras Guanine Nucleotide Exchange Factors
|
|
Concept
|
MAP Kinase Kinase Kinases
|
|
Concept
|
Mutation, Missense
|
|
Concept
|
Chemokine CCL5
|
|
Concept
|
Protein Tyrosine Phosphatases
|
|
Concept
|
GTP Phosphohydrolases
|
|
Concept
|
Reactive Oxygen Species
|
|
Concept
|
In Situ Hybridization, Fluorescence
|
|
Concept
|
Oxazolidinones
|
|
Concept
|
Prostatein
|
|
Concept
|
Primary Cell Culture
|
|
Concept
|
NIH 3T3 Cells
|
|
Concept
|
bcl-2-Associated X Protein
|
|
Concept
|
Cyclin-Dependent Kinase 4
|
|
Concept
|
Chromatin Immunoprecipitation
|
|
Concept
|
Mitogen-Activated Protein Kinase 3
|
|
Concept
|
Mitogen-Activated Protein Kinase 7
|
|
Concept
|
Proto-Oncogene Proteins c-bcl-2
|
|
Concept
|
COS Cells
|
|
Concept
|
Codon, Initiator
|
|
Concept
|
Proto-Oncogene Proteins c-raf
|
|
Concept
|
Amino Acid Substitution
|
|
Concept
|
Proto-Oncogene Proteins B-raf
|
|
Concept
|
Cell Growth Processes
|
|
Concept
|
Caspase 1
|
|
Concept
|
Neovascularization, Physiologic
|
|
Concept
|
Oligonucleotide Array Sequence Analysis
|
|
Concept
|
rac GTP-Binding Proteins
|
|
Concept
|
rap1 GTP-Binding Proteins
|
|
Concept
|
Mitogen-Activated Protein Kinase Kinases
|
|
Concept
|
Active Transport, Cell Nucleus
|
|
Concept
|
Loss of Heterozygosity
|
|
Concept
|
Thrombospondins
|
|
Concept
|
I-kappa B Proteins
|
|
Concept
|
Gene Expression Profiling
|
|
Concept
|
BRCA2 Protein
|
|
Concept
|
Cyclin-Dependent Kinase Inhibitor p21
|
|
Concept
|
bcl-X Protein
|
|
Concept
|
Phenanthridines
|
|
Concept
|
Phosphatidylethanolamines
|
|
Concept
|
Polyisoprenyl Phosphate Oligosaccharides
|
|
Concept
|
Saccharomyces cerevisiae Proteins
|
|
Concept
|
Polyisoprenyl Phosphate Sugars
|
|
Concept
|
Precipitin Tests
|
|
Concept
|
Promoter Regions, Genetic
|
|
Concept
|
Mice
|
|
Concept
|
Prostate
|
|
Concept
|
Radioimmunoassay
|
|
Concept
|
Rats, Inbred Strains
|
|
Concept
|
Ribonucleases
|
|
Concept
|
Saccharomyces cerevisiae
|
|
Concept
|
Syndecan-2
|
|
Concept
|
Glycogen Synthase Kinase 3
|
|
Concept
|
Protein Phosphatase 1
|
|
Concept
|
Stochastic Processes
|
|
Concept
|
Host-Pathogen Interactions
|
|
Concept
|
Shc Signaling Adaptor Proteins
|
|
Concept
|
Rats
|
|
Concept
|
Triazoles
|
|
Concept
|
Real-Time Polymerase Chain Reaction
|
|
Concept
|
Tumor Necrosis Factors
|
|
Concept
|
Trypsin
|
|
Concept
|
MAP Kinase Kinase Kinase 1
|
|
Concept
|
Adaptor Proteins, Signal Transducing
|
|
Concept
|
Temperature
|
|
Concept
|
Immunoblotting
|
|
Concept
|
Blotting, Western
|
|
Concept
|
Down-Regulation
|
|
Concept
|
Inhibitor of Differentiation Protein 1
|
|
Concept
|
Survival Analysis
|
|
Concept
|
Transforming Growth Factor alpha
|
|
Concept
|
Cyclins
|
|
Concept
|
Culture Media, Serum-Free
|
|
Concept
|
Transfection
|
|
Concept
|
Benzophenanthridines
|
|
Concept
|
Tuberous Sclerosis
|
|
Concept
|
Blotting, Southern
|
|
Concept
|
Blotting, Northern
|
|
Concept
|
Reproducibility of Results
|
|
Concept
|
Patient Satisfaction
|
|
Concept
|
Ionomycin
|
|
Concept
|
Gene Expression Regulation, Viral
|
|
Concept
|
Gene Expression Regulation, Enzymologic
|
|
Concept
|
Survival Rate
|
|
Concept
|
Polymerase Chain Reaction
|
|
Concept
|
Amyloid beta-Peptides
|
|
Concept
|
Cyclin-Dependent Kinases
|
|
Concept
|
Stromal Cells
|
|
Concept
|
CD3 Complex
|
|
Concept
|
GTP-Binding Proteins
|
|
Concept
|
NADPH Oxidases
|
|
Concept
|
Cyclin E
|
|
Concept
|
Mitogen-Activated Protein Kinase 1
|
|
Concept
|
Calcium-Calmodulin-Dependent Protein Kinases
|
|
Concept
|
In Situ Nick-End Labeling
|
|
Concept
|
Xenograft Model Antitumor Assays
|
|
Concept
|
Gene Knockdown Techniques
|
|
Concept
|
Serum Response Factor
|
|
Concept
|
Phosphatidylinositol 3-Kinases
|
|
Concept
|
Cyclin A
|
|
Concept
|
JNK Mitogen-Activated Protein Kinases
|
|
Concept
|
Extracellular Signal-Regulated MAP Kinases
|
|
Concept
|
raf Kinases
|
|
Concept
|
Transcriptome
|
|
Concept
|
CASP8 and FADD-Like Apoptosis Regulating Protein
|
|
Concept
|
Insulin Receptor Substrate Proteins
|
|
Concept
|
Tumor Microenvironment
|
|
Concept
|
Ribosomal Protein S6 Kinases, 70-kDa
|
|
Concept
|
Cell Size
|
|
Concept
|
Cell Shape
|
|
Concept
|
14-3-3 Proteins
|
|
Concept
|
Cyclin-Dependent Kinase Inhibitor p27
|
|
Concept
|
bcl-Associated Death Protein
|
|
Concept
|
Genes, Neoplasm
|
|
Concept
|
Kaplan-Meier Estimate
|
|
Concept
|
Protein Phosphatase 2
|
|
Concept
|
Gene Knock-In Techniques
|
|
Concept
|
Genetic Fitness
|
|
Concept
|
Islet Amyloid Polypeptide
|
|
Concept
|
Alzheimer Disease
|
|
Concept
|
Antibodies
|
|
Concept
|
Apgar Score
|
|
Concept
|
Binding, Competitive
|
|
Concept
|
Cell Survival
|
|
Concept
|
Chromatin
|
|
Concept
|
Chromosomes, Human, Pair 16
|
|
Concept
|
Cloning, Molecular
|
|
Concept
|
Disease Models, Animal
|
|
Concept
|
Drug Administration Schedule
|
|
Concept
|
Epidermal Growth Factor
|
|
Concept
|
Glucose
|
|
Concept
|
Growth Substances
|
|
Concept
|
Histidine
|
|
Concept
|
Hyperglycemia
|
|
Concept
|
India
|
|
Concept
|
Kinetics
|
|
Concept
|
Lymphocyte Activation
|
|
Concept
|
Nasolacrimal Duct
|
|
Concept
|
Proto-Oncogenes
|
|
Concept
|
Rats, Mutant Strains
|
|
Concept
|
Receptors, Adrenergic, beta
|
|
Concept
|
Recombinant Fusion Proteins
|
|
Concept
|
Sarcoma Virus, Woolly Monkey
|
|
Concept
|
Staining and Labeling
|
|
Concept
|
T-Lymphocytes
|
|
Concept
|
X Chromosome
|
|
Concept
|
Transcriptional Activation
|
|
Concept
|
Gene Expression Regulation, Neoplastic
|
|
Concept
|
Sequence Analysis, RNA
|
|
Concept
|
Cyclic AMP-Dependent Protein Kinases
|
|
Concept
|
Disease-Free Survival
|
|
Concept
|
Macrolides
|
|
Concept
|
Okadaic Acid
|
|
Concept
|
Cyclin D1
|
|
Concept
|
Genetic Predisposition to Disease
|
|
Concept
|
Oncogene Proteins v-raf
|
|
Concept
|
MicroRNAs
|
|
Concept
|
Mammary Glands, Human
|
|
Concept
|
Protein Kinase Inhibitors
|
|
Concept
|
MAP Kinase Kinase 5
|
|
Concept
|
Cyclin-Dependent Kinase 2
|
|
Concept
|
G-Protein-Coupled Receptor Kinase 2
|
|
Academic Article
|
Insulin-degrading enzyme does not require peroxisomal localization for insulin degradation.
|
|
Academic Article
|
Src tyrosine kinase mediates stimulation of Raf-1 and mitogen-activated protein kinase by the tumor promoter thapsigargin.
|
|
Academic Article
|
The C-terminal domain of human insulin degrading enzyme is required for dimerization and substrate recognition.
|
|
Academic Article
|
Protein kinase C zeta mediates epidermal growth factor-induced growth of head and neck tumor cells by regulating mitogen-activated protein kinase.
|
|
Academic Article
|
NMR assignment of rat Raf kinase inhibitor protein.
|
|
Academic Article
|
tRNA over-expression in breast cancer and functional consequences.
|
|
Academic Article
|
Anthrax edema factor potency depends on mode of cell entry.
|
|
Academic Article
|
Inducible expression and cellular localization of insulin-degrading enzyme in a stably transfected cell line.
|
|
Academic Article
|
Structure-activity studies of the nonphorbol tumor promoter palytoxin in Swiss 3T3 cells.
|
|
Academic Article
|
Signalling pathway for RKIP and Let-7 regulates and predicts metastatic breast cancer.
|
|
Academic Article
|
Histamine antagonizes serotonin and growth factor-induced mitogen-activated protein kinase activation in bovine tracheal smooth muscle cells.
|
|
Academic Article
|
Conditional immortalization of neuronal cells from postmitotic cultures and adult CNS.
|
|
Academic Article
|
Effect of complementary pathway blockade on efficacy of combination enzastaurin and rapamycin.
|
|
Academic Article
|
Identification of zinc ligands of the insulin-degrading enzyme.
|
|
Academic Article
|
Immortal rat hippocampal cell lines exhibit neuronal and glial lineages and neurotrophin gene expression.
|
|
Academic Article
|
Structurally different members of the okadaic acid class selectively inhibit protein serine/threonine but not tyrosine phosphatase activity.
|
|
Academic Article
|
Therapeutic parameters of methylprednisolone treatment for retinal photic injury in a rat model.
|
|
Academic Article
|
Characterization of murine-specific leukemia virus receptor from L cells.
|
|
Academic Article
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Regulation of epidermal growth factor receptor gene expression by retinoic acid and epidermal growth factor.
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Basic and acidic fibroblast growth factors modulate the epidermal growth factor receptor by a protein kinase C-independent pathway.
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Identification of a novel receptor in Drosophila for both epidermal growth factor and insulin.
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Transforming growth factor-beta increases transcription of the genes encoding the epidermal growth factor receptor and fibronectin in normal rat kidney fibroblasts.
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Thapsigargin, a novel promoter, phosphorylates the epidermal growth factor receptor at threonine 669.
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Growth factors modify the epidermal growth factor receptor through multiple pathways.
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Characterization of rodent epidermal growth factor receptor transcripts using a mouse genomic probe.
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Decreased levels of hepatic epidermal growth factor receptors in obese hyperglycemic rodents.
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Characterization of a Drosophila protein that binds both epidermal growth factor and insulin-related growth factors.
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Isolation and characterization of an insulin-degrading enzyme from Drosophila melanogaster.
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Characterization of protein kinase C from normal and transformed cultured murine fibroblasts.
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Tumor promoters block tyrosine-specific phosphorylation of the epidermal growth factor receptor.
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Epidermal growth factor (EGF) receptor T669 peptide kinase from 3T3-L1 cells is an EGF-stimulated "MAP" kinase.
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Two independent growth factor-generated signals regulate c-fos and c-myc mRNA levels in Swiss 3T3 cells.
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Basic fibroblast-like growth factor is present in the conditioned medium of simian sarcoma virus transformed NRK cells.
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Developmental regulation of an insulin-degrading enzyme from Drosophila melanogaster.
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Growth state-dependent regulation of protein kinase C in normal and transformed murine cells.
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Differential Raf requirement for activation of mitogen-activated protein kinase by growth factors, phorbol esters, and calcium.
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Adenovirus and protein kinase C have distinct molecular requirements for regulating epidermal growth factor receptor trafficking.
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N-asparagine-linked oligosaccharides: biosynthesis of the lipid-linked oligosaccharides.
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Insulin-like growth factor I receptor signaling in differentiation of neuronal H19-7 cells.
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Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation.
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Different protein kinase C isoforms determine growth factor specificity in neuronal cells.
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Role of mitogen-activated protein kinase kinase in regulation of the epidermal growth factor receptor by protein kinase C.
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Mutation of Di-leucine residues in the juxtamembrane region alters EGF receptor expression.
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Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line.
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CDKL5/Stk9 kinase inactivation is associated with neuronal developmental disorders.
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Immunohistochemical demonstration of the zinc metalloprotease insulin-degrading enzyme in normal and malignant human breast: correlation with tissue insulin levels.
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Cytoplasmic/nuclear localization of tuberin in different cell lines.
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mTOR phosphorylated at S2448 binds to raptor and rictor.
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Structural changes in intermediate filament networks alter the activity of insulin-degrading enzyme.
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Evidence for cell cycle-dependent, rapamycin-resistant phosphorylation of ribosomal protein S6 at S240/244.
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Tuberous sclerosis causing mutants of the TSC2 gene product affect proliferation and p27 expression.
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Characterization of a Rac1 signaling pathway to cyclin D(1) expression in airway smooth muscle cells.
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Tuberin negatively affects BCL-2's cell survival function.
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Nucleocytoplasmic localization of p70 S6K1, but not of its isoforms p85 and p31, is regulated by TSC2/mTOR.
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Nuclear/cytoplasmic localization of Akt activity in the cell cycle.
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Tuberin, p27 and mTOR in different cells.
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Characterization of a cysteine proteinase inhibitor induced during neuronal cell differentiation.
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Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7.
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14-3-3 proteins are involved in the regulation of mammalian cell proliferation.
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Akt regulates nuclear/cytoplasmic localization of tuberin.
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Expression of metalloprotease insulin-degrading enzyme insulysin in normal and malignant human tissues.
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Immunohistochemical evidence of ubiquitous distribution of the metalloendoprotease insulin-degrading enzyme (IDE; insulysin) in human non-malignant tissues and tumor cell lines.
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CDKs as therapeutic targets for the human genetic disease tuberous sclerosis?
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Purified recombinant insulin-degrading enzyme degrades amyloid beta-protein but does not promote its oligomerization.
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Different cytoplasmic/nuclear distribution of S6 protein phosphorylated at S240/244 and S235/236.
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RKIP and HMGA2 regulate breast tumor survival and metastasis through lysyl oxidase and syndecan-2.
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Gene expression in local stroma reflects breast tumor states and predicts patient outcome.
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Insulin-Degrading Enzyme Does Not Require Peroxisomal Localization for Insulin Degradation.
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Raf kinase inhibitor protein: lessons of a better way for ß-adrenergic receptor activation in the heart.
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Targeting Raf Kinase Inhibitory Protein Regulation and Function.
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Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism.
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Metabolically activated adipose tissue macrophages link obesity to triple-negative breast cancer.
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Observation and Control of Gene Expression Noise: Barrier Crossing Analogies Between Drug Resistance and Metastasis.
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Cannabidiol Inhibits SARS-CoV-2 Replication and Promotes the Host Innate Immune Response.
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Limited inhibition of multiple nodes in a driver network blocks metastasis.
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Tumor Extracellular Vesicles Regulate Macrophage-Driven Metastasis through CCL5.
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New strategies for targeting kinase networks in cancer.
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Cannabidiol inhibits SARS-CoV-2 replication through induction of the host ER stress and innate immune responses.
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Harnessing RKIP to Combat Heart Disease and Cancer.
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Raf Kinase Inhibitory Protein regulates the cAMP-dependent protein kinase signaling pathway through a positive feedback loop.
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SARS-CoV-2 diverges from other betacoronaviruses in only partially activating the IRE1a/XBP1 ER stress pathway in human lung-derived cells.
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SARS-CoV-2 Diverges from Other Betacoronaviruses in Only Partially Activating the IRE1a/XBP1 Endoplasmic Reticulum Stress Pathway in Human Lung-Derived Cells.
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Concept
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Imatinib Mesylate
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Concept
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NF-KappaB Inhibitor alpha
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Concept
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Src Homology 2 Domain-Containing, Transforming Protein 1
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Concept
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Regulatory-Associated Protein of mTOR
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Concept
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Rapamycin-Insensitive Companion of mTOR Protein
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Concept
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Caspase Inhibitors
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Concept
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3-Phosphoinositide-Dependent Protein Kinases
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Academic Article
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Nonmonotone invasion landscape by noise-aware control of metastasis activator levels.
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